An siRNA-guided ARGONAUTE protein directs RNA polymerase V to initiate DNA methylation

In mammals and plants, cytosine DNA methylation is essential for the epigenetic repression of transposable elements and foreign DNA. In plants, DNA methylation is guided by small interfering RNAs (siRNAs) in a self-reinforcing cycle termed RNA-directed DNA methylation (RdDM). RdDM requires the speci...

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Detalles Bibliográficos
Autores principales: Sigman, Meredith J., Panda, Kaushik, Kirchner, Rachel, McLain, Lauren L., Payne, Hayden, Peasari, John Reddy, Husbands, Aman Y., Slotkin, R. Keith, McCue, Andrea D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592841/
https://www.ncbi.nlm.nih.gov/pubmed/34750500
http://dx.doi.org/10.1038/s41477-021-01008-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592841/
https://www.ncbi.nlm.nih.gov/pubmed/34750500
http://dx.doi.org/10.1038/s41477-021-01008-7

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