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Temperature effect on polymerase fidelity

The discovery of extremophiles helped enable the development of groundbreaking technology such as PCR. Temperature variation is often an essential step of these technology platforms, but the effect of temperature on the error rate of polymerases from different origins is underexplored. Here, we appl...

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Detalles Bibliográficos
Autores principales: Xue, Yuan, Braslavsky, Ido, Quake, Stephen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592868/
https://www.ncbi.nlm.nih.gov/pubmed/34695416
http://dx.doi.org/10.1016/j.jbc.2021.101270