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Temperature effect on polymerase fidelity
The discovery of extremophiles helped enable the development of groundbreaking technology such as PCR. Temperature variation is often an essential step of these technology platforms, but the effect of temperature on the error rate of polymerases from different origins is underexplored. Here, we appl...
Autores principales: | Xue, Yuan, Braslavsky, Ido, Quake, Stephen R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592868/ https://www.ncbi.nlm.nih.gov/pubmed/34695416 http://dx.doi.org/10.1016/j.jbc.2021.101270 |
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