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Beta turn propensity and a model polymer scaling exponent identify intrinsically disordered phase-separating proteins

The complex cellular milieu can spontaneously demix, or phase separate, in a process controlled in part by intrinsically disordered (ID) proteins. A protein's propensity to phase separate is thought to be driven by a preference for protein–protein over protein–solvent interactions. The hydrodyn...

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Detalles Bibliográficos
Autores principales: Paiz, Elisia A., Allen, Jeffre H., Correia, John J., Fitzkee, Nicholas C., Hough, Loren E., Whitten, Steven T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592878/
https://www.ncbi.nlm.nih.gov/pubmed/34710373
http://dx.doi.org/10.1016/j.jbc.2021.101343