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Dihydroartemisinin Suppresses the Tumorigenesis and Cycle Progression of Colorectal Cancer by Targeting CDK1/CCNB1/PLK1 Signaling

Dihydroartemisinin (DHA), a well-known antimalarial drug, has been widely investigated for its antitumor effects in multiple malignancies. However, its effects and regulatory mechanisms in colorectal cancer (CRC) are still unproved. In this study, in vitro experiments including CCK8, EdU, Transwell,...

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Detalles Bibliográficos
Autores principales: Yi, You-Cai, Liang, Rui, Chen, Xiao-Yu, Fan, Hui-Ning, Chen, Ming, Zhang, Jing, Zhu, Jin-Shui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592930/
https://www.ncbi.nlm.nih.gov/pubmed/34796115
http://dx.doi.org/10.3389/fonc.2021.768879