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Dihydroartemisinin Suppresses the Tumorigenesis and Cycle Progression of Colorectal Cancer by Targeting CDK1/CCNB1/PLK1 Signaling
Dihydroartemisinin (DHA), a well-known antimalarial drug, has been widely investigated for its antitumor effects in multiple malignancies. However, its effects and regulatory mechanisms in colorectal cancer (CRC) are still unproved. In this study, in vitro experiments including CCK8, EdU, Transwell,...
Autores principales: | Yi, You-Cai, Liang, Rui, Chen, Xiao-Yu, Fan, Hui-Ning, Chen, Ming, Zhang, Jing, Zhu, Jin-Shui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592930/ https://www.ncbi.nlm.nih.gov/pubmed/34796115 http://dx.doi.org/10.3389/fonc.2021.768879 |
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