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Deletion of AMPA receptor GluA1 subunit gene (Gria1) causes circadian rhythm disruption and aberrant responses to environmental cues

Dysfunction of the glutamate α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor GluA1 subunit and deficits in synaptic plasticity are implicated in schizophrenia and sleep and circadian rhythm disruption. To investigate the role of GluA1 in circadian and sleep behaviour, we used wh...

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Detalles Bibliográficos
Autores principales: Ang, Gauri, Brown, Laurence A., Tam, Shu K. E., Davies, Kay E., Foster, Russell G., Harrison, Paul J., Sprengel, Rolf, Vyazovskiy, Vladyslav V., Oliver, Peter L., Bannerman, David M., Peirson, Stuart N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593011/
https://www.ncbi.nlm.nih.gov/pubmed/34782594
http://dx.doi.org/10.1038/s41398-021-01690-3