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Gestational Diabetes Mellitus-Associated Hyperglycemia Impairs Glucose Transporter 3 Trafficking in Trophoblasts Through the Downregulation of AMP-Activated Protein Kinase

AMP-activated protein kinase (AMPK) is an important regulator of glucose metabolism, and glucose transporter 3 (GLUT3) is an efficient glucose transporter in trophoblasts. Whether placental AMPK and GLUT3 respond accordingly to gestational diabetes mellitus (GDM) remains uncertain. Here, we explored...

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Detalles Bibliográficos
Autores principales: Zhang, Li, Yu, Xinyang, Wu, Yue, Fu, Huijia, Xu, Ping, Zheng, Yangxi, Wen, Li, Yang, Xiaotao, Zhang, Fumei, Hu, Mingyu, Wang, Hao, Liu, Xiyao, Qiao, Juan, Peng, Chuan, Gao, Rufei, Saffery, Richard, Fu, Yong, Qi, Hongbo, Tong, Chao, Kilby, Mark D., Baker, Philip N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593042/
https://www.ncbi.nlm.nih.gov/pubmed/34796169
http://dx.doi.org/10.3389/fcell.2021.722024