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Identification of ASCL1 as a determinant for human iPSC-derived dopaminergic neurons

During cellular specification, transcription factors orchestrate cellular decisions through gene regulation. By hijacking these transcriptional networks, human pluripotent stem cells (hPSCs) can be specialized into neurons with different molecular identities for the purposes of regenerative medicine...

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Detalles Bibliográficos
Autores principales: Earley, Aaron M., Burbulla, Lena F., Krainc, Dimitri, Awatramani, Rajeshwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593045/
https://www.ncbi.nlm.nih.gov/pubmed/34782629
http://dx.doi.org/10.1038/s41598-021-01366-4