Bi-allelic variants in human WDR63 cause male infertility via abnormal inner dynein arms assembly

Inner dynein arm (IDA), composed of a series of protein complex, is necessary to cilia and flagella bend formation and beating. Previous studies indicated that defects of IDA protein complex result in multiple morphological abnormalities of the sperm flagellum (MMAF) and male infertility. However, t...

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Detalles Bibliográficos
Autores principales: Lu, Shuai, Gu, Yayun, Wu, Yifei, Yang, Shenmin, Li, Chenmeijie, Meng, Lanlan, Yuan, Wenwen, Jiang, Tao, Zhang, Xin, Li, Yang, Wang, Cheng, Liu, Mingxi, Ye, Lan, Guo, Xuejiang, Shen, Hongbing, Yang, Xiaoyu, Tan, Yueqiu, Hu, Zhibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593051/
https://www.ncbi.nlm.nih.gov/pubmed/34782613
http://dx.doi.org/10.1038/s41421-021-00327-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593051/
https://www.ncbi.nlm.nih.gov/pubmed/34782613
http://dx.doi.org/10.1038/s41421-021-00327-5

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