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BH3-only proteins Puma and Beclin1 regulate autophagic death in neurons in response to Amyloid-β
Alzheimer’s disease (AD) is characterized by accumulation of senile amyloid-β (Aβ) plaques and hyperphosphorylated tau tangles causing progressive loss of synapse and neuronal death. Out of the various neuron death modalities, autophagy and apoptosis are reported to be the major death paradigms in A...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593071/ https://www.ncbi.nlm.nih.gov/pubmed/34782612 http://dx.doi.org/10.1038/s41420-021-00748-x |