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Enhanced Migratory Capacity of T Lymphocytes in Severe Chagasic Patients Is Correlated With VLA-4 and TNF-α Expression

Trypanosoma cruzi infection in humans leads to progression to chronic chagasic myocarditis (CCM) in 30% of infected individuals, paralleling T cell inflammatory infiltrates in the heart tissue. T-cell trafficking into the hearts of CCM patients may be modulated by in situ expression of chemotactic o...

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Detalles Bibliográficos
Autores principales: Berbert, Luiz Ricardo, González, Florencia Belén, Villar, Silvina Raquel, Vigliano, Carlos, Lioi, Susana, Beloscar, Juan, Bottasso, Oscar Adelmo, Silva-Barbosa, Suse Dayse, Savino, Wilson, Pérez, Ana Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593233/
https://www.ncbi.nlm.nih.gov/pubmed/34796122
http://dx.doi.org/10.3389/fcimb.2021.713150