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Ets-2 Propagates IL-6 Trans-Signaling Mediated Osteoclast-Like Changes in Human Rheumatoid Arthritis Synovial Fibroblast

Rheumatoid arthritis synovial fibroblasts (RASFs) contribute to synovial inflammation and bone destruction by producing a pleiotropic cytokine interleukin-6 (IL-6). However, the molecular mechanisms through which IL-6 propels RASFs to contribute to bone loss are not fully understood. In the present...

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Detalles Bibliográficos
Autores principales: Singh, Anil K., Haque, Mahamudul, Madarampalli, Bhanupriya, Shi, Yuanyuan, Wildman, Benjamin J., Basit, Abdul, Khuder, Sadik A., Prasad, Bhagwat, Hassan, Quamarul, Ouseph, Madhu M., Ahmed, Salahuddin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593237/
https://www.ncbi.nlm.nih.gov/pubmed/34795667
http://dx.doi.org/10.3389/fimmu.2021.746503