HIV-1 Env Does Not Enable the Development of Protective Broadly Neutralizing Antibodies in an Experimental Autoimmune Encephalomyelitis Mouse Model

Recent studies showed that immunological tolerance may restrict the development of Env-specific autoreactive broadly neutralizing antibodies. This evidence is consistent with the finding that Env immunization of a systemic lupus erythematosus (SLE) murine model produced antibodies that neutralize ti...

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Detalles Bibliográficos
Autores principales: Siracusano, Gabriel, Finardi, Annamaria, Pastori, Claudia, Martinelli, Vittorio, Furlan, Roberto, Lopalco, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593332/
https://www.ncbi.nlm.nih.gov/pubmed/34795677
http://dx.doi.org/10.3389/fimmu.2021.771359