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High concentration of extracellular nucleotides suppresses cell growth via delayed cell cycle progression in cancer and noncancer cell lines

Tumor necrosis frequently occurs in malignant tumors, showing rapid growth and invasion. This phenomenon is generally regarded as simple ischemic necrosis due to insufficient tumor vessels and blood supply. However, the necrotic tissue contains high amount of nuclear substances, DNA, and nucleoprote...

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Detalles Bibliográficos
Autores principales: Sawa, Chika, Yofu, Sachiko, Kiriyama, Keisuke, Sutoh, Keita, Saito, Tomomi, Kishi, Satomi, Gunji, Mariko, Inoue, Yuriko, Sugi, Masahito, Shioda, Seiji, Honda, Kazuho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593434/
https://www.ncbi.nlm.nih.gov/pubmed/34816032
http://dx.doi.org/10.1016/j.heliyon.2021.e08318