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Involvement of RIG-I Pathway in Neurotropic Virus-Induced Acute Flaccid Paralysis and Subsequent Spinal Motor Neuron Death

Poliomyelitis-like illness is a common clinical manifestation of neurotropic viral infections. Functional loss and death of motor neurons often lead to reduced muscle tone and paralysis, causing persistent motor sequelae among disease survivors. Despite several reports demonstrating the molecular ba...

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Detalles Bibliográficos
Autores principales: Bhaskar, Meenakshi, Mukherjee, Sriparna, Basu, Anirban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593677/
https://www.ncbi.nlm.nih.gov/pubmed/34781742
http://dx.doi.org/10.1128/mBio.02712-21