25-Hydroxycholesterol Inhibits Kaposi’s Sarcoma Herpesvirus and Epstein-Barr Virus Infections and Activates Inflammatory Cytokine Responses

Oncogenic gammaherpesviruses express viral products during latent and lytic infection that block the innate immune response. Previously, we found that Kaposi’s sarcoma herpesvirus (KSHV/human herpesvirus-8) viral microRNAs (miRNAs) downregulate cholesterol biogenesis, and we hypothesized that this p...

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Detalles Bibliográficos
Autores principales: Serquiña, Anna K. P., Tagawa, Takanobu, Oh, Daniel, Mahesh, Guruswamy, Ziegelbauer, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593836/
https://www.ncbi.nlm.nih.gov/pubmed/34781692
http://dx.doi.org/10.1128/mBio.02907-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593836/
https://www.ncbi.nlm.nih.gov/pubmed/34781692
http://dx.doi.org/10.1128/mBio.02907-21

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