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25-Hydroxycholesterol Inhibits Kaposi’s Sarcoma Herpesvirus and Epstein-Barr Virus Infections and Activates Inflammatory Cytokine Responses
Oncogenic gammaherpesviruses express viral products during latent and lytic infection that block the innate immune response. Previously, we found that Kaposi’s sarcoma herpesvirus (KSHV/human herpesvirus-8) viral microRNAs (miRNAs) downregulate cholesterol biogenesis, and we hypothesized that this p...
Autores principales: | Serquiña, Anna K. P., Tagawa, Takanobu, Oh, Daniel, Mahesh, Guruswamy, Ziegelbauer, Joseph M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593836/ https://www.ncbi.nlm.nih.gov/pubmed/34781692 http://dx.doi.org/10.1128/mBio.02907-21 |
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