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Comparison of SHANK3 deficiency in animal models: phenotypes, treatment strategies, and translational implications

BACKGROUND: Autism spectrum disorder (ASD) is a neurodevelopmental condition, which is characterized by clinical heterogeneity and high heritability. Core symptoms of ASD include deficits in social communication and interaction, as well as restricted, repetitive patterns of behavior, interests, or a...

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Detalles Bibliográficos
Autores principales: Delling, Jan Philipp, Boeckers, Tobias M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594088/
https://www.ncbi.nlm.nih.gov/pubmed/34784886
http://dx.doi.org/10.1186/s11689-021-09397-8