Chemogenetic modulation of sensory neurons reveals their regulating role in melanoma progression

Sensory neurons have recently emerged as components of the tumor microenvironment. Nevertheless, whether sensory neuronal activity is important for tumor progression remains unknown. Here we used Designer Receptors Exclusively Activated by a Designer Drug (DREADD) technology to inhibit or activate s...

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Detalles Bibliográficos
Autores principales: Costa, Pedro A. C., Silva, Walison N., Prazeres, Pedro H. D. M., Picoli, Caroline C., Guardia, Gabriela D. A., Costa, Alinne C., Oliveira, Mariana A., Guimarães, Pedro P. G., Gonçalves, Ricardo, Pinto, Mauro C. X., Amorim, Jaime H., Azevedo, Vasco A. C., Resende, Rodrigo R., Russo, Remo C., Cunha, Thiago M., Galante, Pedro A. F., Mintz, Akiva, Birbrair, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594104/
https://www.ncbi.nlm.nih.gov/pubmed/34784974
http://dx.doi.org/10.1186/s40478-021-01273-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594104/
https://www.ncbi.nlm.nih.gov/pubmed/34784974
http://dx.doi.org/10.1186/s40478-021-01273-9

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