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IRF7 and RNH1 are modifying factors of HIV-1 reservoirs: a genome-wide association analysis

BACKGROUND: Combination antiretroviral treatment (cART) cannot eradicate HIV-1 from the body due to the establishment of persisting viral reservoirs which are not affected by therapy and reinitiate new rounds of HIV-1 replication after treatment interruption. These HIV-1 reservoirs mainly comprise l...

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Detalles Bibliográficos
Autores principales: Zhang, Zhenhua, Trypsteen, Wim, Blaauw, Marc, Chu, Xiaojing, Rutsaert, Sofie, Vandekerckhove, Linos, van der Heijden, Wouter, dos Santos, Jéssica Cristina, Xu, Cheng-Jian, Swertz, Morris A., van der Ven, Andre, Li, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594146/
https://www.ncbi.nlm.nih.gov/pubmed/34781942
http://dx.doi.org/10.1186/s12916-021-02156-5