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Presenilin1 inhibits glioblastoma cell invasiveness via promoting Sortilin cleavage

BACKGROUND: Alzheimer’s disease (AD) and glioblastoma are the most common and devastating diseases in the neurology and neurosurgery departments, respectively. Our previous research reports that the AD-related protein Presenilin1 represses cell proliferation by inhibiting the Wnt/β-catenin pathway i...

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Detalles Bibliográficos
Autores principales: Yang, Wei, Xiang, Yan, Liao, Mao-Jun, Wu, Peng-Fei, Yang, Lin, Huang, Guo-Hao, Shi, Bao-Zhong, Yi, Liang, Lv, Sheng-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594175/
https://www.ncbi.nlm.nih.gov/pubmed/34781973
http://dx.doi.org/10.1186/s12964-021-00780-5