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A comparative analysis of L1 retrotransposition activities in human genomes suggests an ongoing increase in L1 number despite an evolutionary trend towards lower activity

BACKGROUND: LINE-1 (Long Interspersed Nuclear Elements, L1) retrotransposons are the only autonomously active transposable elements in the human genome. The evolution of L1 retrotransposition rates and its implications for L1 dynamics are poorly understood. Retrotransposition rates are commonly meas...

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Detalles Bibliográficos
Autores principales: Wehbi, Sawsan Sami, zu Dohna, Heinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594186/
https://www.ncbi.nlm.nih.gov/pubmed/34782009
http://dx.doi.org/10.1186/s13100-021-00255-x