Epigenetic Regulation of EMT (Epithelial to Mesenchymal Transition) and Tumor Aggressiveness: A View on Paradoxical Roles of KDM6B and EZH2

EMT (epithelial to mesenchymal transition) is a plastic phenomenon involved in metastasis formation. Its plasticity is conferred in a great part by its epigenetic regulation. It has been reported that the trimethylation of lysine 27 histone H3 (H3K27me3) was a master regulator of EMT through two ant...

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Detalles Bibliográficos
Autores principales: Lachat, Camille, Boyer-Guittaut, Michaël, Peixoto, Paul, Hervouet, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594212/
https://www.ncbi.nlm.nih.gov/pubmed/34991274
http://dx.doi.org/10.3390/epigenomes3010001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594212/
https://www.ncbi.nlm.nih.gov/pubmed/34991274
http://dx.doi.org/10.3390/epigenomes3010001

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