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Expansion of myeloid-derived suppressor cells contributes to metabolic osteoarthritis through subchondral bone remodeling

BACKGROUND: Osteoarthritis (OA) subsequent to acute joint injury accounts for a significant proportion of all arthropathies. Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of myeloid progenitor cells classically known for potent immune-suppressive activity; however, MDSCs ca...

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Detalles Bibliográficos
Autores principales: Zhang, Lixia, Kirkwood, Cameron L., Sohn, Jiho, Lau, Ashley, Bayers-Thering, Mary, Bali, Supinder Kour, Rachala, Sridhar, Marzo, John M., Anders, Mark J., Beier, Frank, Kirkwood, Keith L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594239/
https://www.ncbi.nlm.nih.gov/pubmed/34784965
http://dx.doi.org/10.1186/s13075-021-02663-z