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The kinesin KIF1C transports APC-dependent mRNAs to cell protrusions

RNA localization and local translation are important for numerous cellular functions. In mammals, a class of mRNAs localize to cytoplasmic protrusions in an APC-dependent manner, with roles during cell migration. Here, we investigated this localization mechanism. We found that the KIF1C motor intera...

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Detalles Bibliográficos
Autores principales: Pichon, Xavier, Moissoglu, Konstadinos, Coleno, Emeline, Wang, Tianhong, Imbert, Arthur, Robert, Marie-Cécile, Peter, Marion, Chouaib, Racha, Walter, Thomas, Mueller, Florian, Zibara, Kazem, Bertrand, Edouard, Mili, Stavroula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594469/
https://www.ncbi.nlm.nih.gov/pubmed/34493599
http://dx.doi.org/10.1261/rna.078576.120