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Scanning mutagenesis of RNA-binding protein ProQ reveals a quality control role for the Lon protease

The FinO-domain protein ProQ belongs to a widespread family of RNA-binding proteins (RBPs) involved in gene regulation in bacterial chromosomes and mobile elements. While the cellular RNA targets of ProQ have been established in diverse bacteria, the functionally crucial ProQ residues remain to be i...

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Detalles Bibliográficos
Autores principales: El Mouali, Youssef, Ponath, Falk, Scharrer, Vinzent, Wenner, Nicolas, Hinton, Jay C.D., Vogel, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594473/
https://www.ncbi.nlm.nih.gov/pubmed/34497069
http://dx.doi.org/10.1261/rna.078954.121