A survey of RNA editing at single-cell resolution links interneurons to schizophrenia and autism

Conversion of adenosine to inosine in RNA by ADAR enzymes, termed “RNA editing,” is essential for healthy brain development. Editing is dysregulated in neuropsychiatric diseases, but has not yet been investigated at scale at the level of individual neurons. We quantified RNA editing sites in nuclear...

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Detalles Bibliográficos
Autores principales: Ansell, Brendan Robert E., Thomas, Simon N., Bonelli, Roberto, Munro, Jacob E., Freytag, Saskia, Bahlo, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594476/
https://www.ncbi.nlm.nih.gov/pubmed/34535545
http://dx.doi.org/10.1261/rna.078804.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594476/
https://www.ncbi.nlm.nih.gov/pubmed/34535545
http://dx.doi.org/10.1261/rna.078804.121

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