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A survey of RNA editing at single-cell resolution links interneurons to schizophrenia and autism
Conversion of adenosine to inosine in RNA by ADAR enzymes, termed “RNA editing,” is essential for healthy brain development. Editing is dysregulated in neuropsychiatric diseases, but has not yet been investigated at scale at the level of individual neurons. We quantified RNA editing sites in nuclear...
Autores principales: | Ansell, Brendan Robert E., Thomas, Simon N., Bonelli, Roberto, Munro, Jacob E., Freytag, Saskia, Bahlo, Melanie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594476/ https://www.ncbi.nlm.nih.gov/pubmed/34535545 http://dx.doi.org/10.1261/rna.078804.121 |
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