Low-bias ncRNA libraries using ordered two-template relay: Serial template jumping by a modified retroelement reverse transcriptase

Selfish, non-long terminal repeat (non-LTR) retroelements and mobile group II introns encode reverse transcriptases (RTs) that can initiate DNA synthesis without substantial base pairing of primer and template. Biochemical characterization of these enzymes has been limited by recombinant expression...

Descripción completa

Detalles Bibliográficos
Autores principales: Upton, Heather E., Ferguson, Lucas, Temoche-Diaz, Morayma M., Liu, Xiao-Man, Pimentel, Sydney C., Ingolia, Nicholas T., Schekman, Randy, Collins, Kathleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594491/
https://www.ncbi.nlm.nih.gov/pubmed/34649994
http://dx.doi.org/10.1073/pnas.2107900118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594491/
https://www.ncbi.nlm.nih.gov/pubmed/34649994
http://dx.doi.org/10.1073/pnas.2107900118

Ejemplares similares