Computational prediction of the effect of amino acid changes on the binding affinity between SARS-CoV-2 spike RBD and human ACE2

The association of the receptor binding domain (RBD) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein with human angiotensin-converting enzyme 2 (hACE2) represents the first required step for cellular entry. SARS-CoV-2 has continued to evolve with the emergence of severa...

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Detalles Bibliográficos
Autores principales: Chen, Chen, Boorla, Veda Sheersh, Banerjee, Deepro, Chowdhury, Ratul, Cavener, Victoria S., Nissly, Ruth H., Gontu, Abhinay, Boyle, Nina R., Vandegrift, Kurt, Nair, Meera Surendran, Kuchipudi, Suresh V., Maranas, Costas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Physical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594574/
https://www.ncbi.nlm.nih.gov/pubmed/34588290
http://dx.doi.org/10.1073/pnas.2106480118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594574/
https://www.ncbi.nlm.nih.gov/pubmed/34588290
http://dx.doi.org/10.1073/pnas.2106480118

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