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Computational prediction of the effect of amino acid changes on the binding affinity between SARS-CoV-2 spike RBD and human ACE2

The association of the receptor binding domain (RBD) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein with human angiotensin-converting enzyme 2 (hACE2) represents the first required step for cellular entry. SARS-CoV-2 has continued to evolve with the emergence of severa...

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Detalles Bibliográficos
Autores principales:	Chen, Chen, Boorla, Veda Sheersh, Banerjee, Deepro, Chowdhury, Ratul, Cavener, Victoria S., Nissly, Ruth H., Gontu, Abhinay, Boyle, Nina R., Vandegrift, Kurt, Nair, Meera Surendran, Kuchipudi, Suresh V., Maranas, Costas D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2021
Materias:	Physical Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594574/ https://www.ncbi.nlm.nih.gov/pubmed/34588290 http://dx.doi.org/10.1073/pnas.2106480118

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