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A flexible GAS belt responds to pore mutations changing the ion selectivity of proton-gated channels
Proton-gated ion channels conduct mainly Na(+) to induce postsynaptic membrane depolarization. Finding the determinants of ion selectivity requires knowledge of the pore structure in the open conformation, but such information is not yet available. Here, the open conformation of the hASIC1a channel...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594623/ https://www.ncbi.nlm.nih.gov/pubmed/34766968 http://dx.doi.org/10.1085/jgp.202112978 |