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Targeting the RNA-Binding Protein QKI in Myeloid Cells Ameliorates Macrophage-Induced Renal Interstitial Fibrosis

In the pathophysiologic setting of acute and chronic kidney injury, the excessive activation and recruitment of blood-borne monocytes prompts their differentiation into inflammatory macrophages, a process that leads to progressive glomerulosclerosis and interstitial fibrosis. Importantly, this diffe...

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Detalles Bibliográficos
Autores principales: de Bruin, Ruben G., Vogel, Gillian, Prins, Jurrien, Duijs, Jacques M. J. G., Bijkerk, Roel, van der Zande, Hendrik J. P., van Gils, Janine M., de Boer, Hetty C., Rabelink, Ton J., van Zonneveld, Anton Jan, van der Veer, Eric P., Richard, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594696/
https://www.ncbi.nlm.nih.gov/pubmed/34968236
http://dx.doi.org/10.3390/epigenomes4010002