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5-Methylcytosine and 5-Hydroxymethylcytosine Signatures Underlying Pediatric Cancers

In addition to the genetic variations, recent evidence has shown that DNA methylation of both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) underlies the pathogenesis of pediatric cancer. Given the high mortality rate, there is an urgent need to study the mechanisms contributing to the p...

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Detalles Bibliográficos
Autores principales: Jhanwar, Shalu, Deogade, Ajinkya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594703/
https://www.ncbi.nlm.nih.gov/pubmed/34968232
http://dx.doi.org/10.3390/epigenomes3020009