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The chromatin insulator CTCF regulates HPV18 transcript splicing and differentiation-dependent late gene expression

The ubiquitous host protein, CCCTC-binding factor (CTCF), is an essential regulator of cellular transcription and functions to maintain epigenetic boundaries, stabilise chromatin loops and regulate splicing of alternative exons. We have previously demonstrated that CTCF binds to the E2 open reading...

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Detalles Bibliográficos
Autores principales: Ferguson, Jack, Campos-León, Karen, Pentland, Ieisha, Stockton, Joanne D., Günther, Thomas, Beggs, Andrew D., Grundhoff, Adam, Roberts, Sally, Noyvert, Boris, Parish, Joanna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594839/
https://www.ncbi.nlm.nih.gov/pubmed/34735550
http://dx.doi.org/10.1371/journal.ppat.1010032