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The chromatin insulator CTCF regulates HPV18 transcript splicing and differentiation-dependent late gene expression
The ubiquitous host protein, CCCTC-binding factor (CTCF), is an essential regulator of cellular transcription and functions to maintain epigenetic boundaries, stabilise chromatin loops and regulate splicing of alternative exons. We have previously demonstrated that CTCF binds to the E2 open reading...
Autores principales: | Ferguson, Jack, Campos-León, Karen, Pentland, Ieisha, Stockton, Joanne D., Günther, Thomas, Beggs, Andrew D., Grundhoff, Adam, Roberts, Sally, Noyvert, Boris, Parish, Joanna L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594839/ https://www.ncbi.nlm.nih.gov/pubmed/34735550 http://dx.doi.org/10.1371/journal.ppat.1010032 |
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