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Metatranscriptomics to characterize respiratory virome, microbiome, and host response directly from clinical samples

We developed a metatranscriptomics method that can simultaneously capture the respiratory virome, microbiome, and host response directly from low biomass samples. Using nasal swab samples, we capture RNA virome with sufficient sequencing depth required to assemble complete genomes. We find a surpris...

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Detalles Bibliográficos
Autores principales: Rajagopala, Seesandra V., Bakhoum, Nicole G., Pakala, Suman B., Shilts, Meghan H., Rosas-Salazar, Christian, Mai, Annie, Boone, Helen H., McHenry, Rendie, Yooseph, Shibu, Halasa, Natasha, Das, Suman R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594859/
https://www.ncbi.nlm.nih.gov/pubmed/34790908
http://dx.doi.org/10.1016/j.crmeth.2021.100091