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Comparative Physical Study of Three Pharmaceutically Active Benzodiazepine Derivatives: Crystalline versus Amorphous State and Crystallization Tendency
[Image: see text] Chemical derivatization and amorphization are two possible strategies to improve the solubility and bioavailability of drugs, which is a key issue for the pharmaceutical industry. In this contribution, we explore whether both strategies can be combined by studying how small differe...
Autores principales: | Valenti, Sofia, Barrio, Maria, Negrier, Philippe, Romanini, Michela, Macovez, Roberto, Tamarit, Josep-Lluis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594866/ https://www.ncbi.nlm.nih.gov/pubmed/33689364 http://dx.doi.org/10.1021/acs.molpharmaceut.1c00081 |
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