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Intestinal goblet cells sample and deliver lumenal antigens by regulated endocytic uptake and transcytosis

Intestinal goblet cells maintain the protective epithelial barrier through mucus secretion and yet sample lumenal substances for immune processing through formation of goblet cell associated antigen passages (GAPs). The cellular biology of GAPs and how these divergent processes are balanced and regu...

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Detalles Bibliográficos
Autores principales: Gustafsson, Jenny K, Davis, Jazmyne E, Rappai, Tracy, McDonald, Keely G, Kulkarni, Devesha H, Knoop, Kathryn A, Hogan, Simon P, Fitzpatrick, James AJ, Lencer, Wayne I, Newberry, Rodney D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594945/
https://www.ncbi.nlm.nih.gov/pubmed/34677124
http://dx.doi.org/10.7554/eLife.67292