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Distinctive Signaling Profiles With Distinct Biological and Clinical Implications in Aggressive CLL Subsets With Stereotyped B-Cell Receptor Immunoglobulin

The ontogeny and evolution of chronic lymphocytic leukemia (CLL) are critically dependent on interactions between leukemic cells and their microenvironment, including antigens, the latter recognized through the clonotypic B-cell receptor immunoglobulin (BcR IG). Antigen selection is key to the patho...

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Detalles Bibliográficos
Autores principales: Gerousi, Marina, Laidou, Stamatia, Gemenetzi, Katerina, Stamatopoulos, Kostas, Chatzidimitriou, Anastasia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595110/
https://www.ncbi.nlm.nih.gov/pubmed/34804974
http://dx.doi.org/10.3389/fonc.2021.771454