(-)-T-Cadinol—a Sesquiterpene Isolated From Casearia sylvestris (Salicaceae)—Displayed In Vitro Activity and Causes Hyperpolarization of the Membrane Potential of Trypanosoma cruzi

Chagas disease is caused by the protozoan parasite Trypanosoma cruzi and affects 6–8 million people worldwide, mainly from developing countries. The treatment is limited to two approved nitro-derivatives, nifurtimox and benznidazole, with several side effects and reduced efficacy. Casearia sylvestri...

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Detalles Bibliográficos
Autores principales: dos Santos, Augusto L., Amaral, Maiara, Hasegawa, Flavia Rie, Lago, João Henrique G., Tempone, Andre G., Sartorelli, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595124/
https://www.ncbi.nlm.nih.gov/pubmed/34803682
http://dx.doi.org/10.3389/fphar.2021.734127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595124/
https://www.ncbi.nlm.nih.gov/pubmed/34803682
http://dx.doi.org/10.3389/fphar.2021.734127

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