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Efficacy of booster doses in augmenting waning immune responses to COVID-19 vaccine in patients with cancer

Anti-COVID-19 immunity dynamics were assessed in patients with cancer in a prospective clinical trial. Waning of immunity was detected 4-6 months post-vaccination with significant increases in anti-spike IgG titers after booster dosing, and 56% of seronegative patients seroconverted post-booster vac...

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Detalles Bibliográficos
Autores principales: Shapiro, Lauren C., Thakkar, Astha, Campbell, Sean T., Forest, Stefanie K., Pradhan, Kith, Gonzalez-Lugo, Jesus D., Quinn, Ryann, Bhagat, Tushar D., Choudhary, Gaurav S., McCort, Margaret, Sica, R. Alejandro, Goldfinger, Mendel, Goel, Swati, Anampa, Jesus D., Levitz, David, Fromowitz, Ariel, Shah, Akash Pradip, Sklow, Charlotte, Alfieri, Gregory, Racine, Andrew, Wolgast, Lucia, Greenberger, Lee, Verma, Amit, Halmos, Balazs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595142/
https://www.ncbi.nlm.nih.gov/pubmed/34838186
http://dx.doi.org/10.1016/j.ccell.2021.11.006