Mitochondrial Defects in Fibroblasts of Pathogenic MAPT Patients

Mutations in MAPT gene cause multiple neurological disorders, including frontal temporal lobar degeneration and parkinsonism. Increasing evidence indicates impaired mitochondrial homeostasis and mitophagy in patients and disease models of pathogenic MAPT. Here, using MAPT patients’ fibroblasts as a...

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Detalles Bibliográficos
Autores principales: Bharat, Vinita, Hsieh, Chung-Han, Wang, Xinnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595217/
https://www.ncbi.nlm.nih.gov/pubmed/34805172
http://dx.doi.org/10.3389/fcell.2021.765408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595217/
https://www.ncbi.nlm.nih.gov/pubmed/34805172
http://dx.doi.org/10.3389/fcell.2021.765408

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