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Methods to Develop an in silico Clinical Trial: Computational Head-to-Head Comparison of Lisdexamfetamine and Methylphenidate

Regulatory agencies encourage computer modeling and simulation to reduce the time and cost of clinical trials. Although still not classified in formal guidelines, system biology-based models represent a powerful tool for generating hypotheses with great molecular detail. Herein, we have applied a me...

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Detalles Bibliográficos
Autores principales: Gutiérrez-Casares, José Ramón, Quintero, Javier, Jorba, Guillem, Junet, Valentin, Martínez, Vicente, Pozo-Rubio, Tamara, Oliva, Baldomero, Daura, Xavier, Mas, José Manuel, Montoto, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595241/
https://www.ncbi.nlm.nih.gov/pubmed/34803764
http://dx.doi.org/10.3389/fpsyt.2021.741170