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Methods to Develop an in silico Clinical Trial: Computational Head-to-Head Comparison of Lisdexamfetamine and Methylphenidate
Regulatory agencies encourage computer modeling and simulation to reduce the time and cost of clinical trials. Although still not classified in formal guidelines, system biology-based models represent a powerful tool for generating hypotheses with great molecular detail. Herein, we have applied a me...
Autores principales: | Gutiérrez-Casares, José Ramón, Quintero, Javier, Jorba, Guillem, Junet, Valentin, Martínez, Vicente, Pozo-Rubio, Tamara, Oliva, Baldomero, Daura, Xavier, Mas, José Manuel, Montoto, Carmen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595241/ https://www.ncbi.nlm.nih.gov/pubmed/34803764 http://dx.doi.org/10.3389/fpsyt.2021.741170 |
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