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BRAF Signaling Inhibition in Glioblastoma: Which Clinical Perspectives?

IDH-wild type (wt) glioblastoma (GB) accounts for approximately 90% of all GB and has a poor outcome. Surgery and adjuvant therapy with temozolomide and radiotherapy is the main therapeutic approach. Unfortunately, after relapse and progression, which occurs in most cases, there are very limited the...

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Detalles Bibliográficos
Autores principales: Bouchè, Victoria, Aldegheri, Giovanni, Donofrio, Carmine Antonio, Fioravanti, Antonio, Roberts-Thomson, Samuel, Fox, Stephen B., Schettini, Francesco, Generali, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595319/
https://www.ncbi.nlm.nih.gov/pubmed/34804975
http://dx.doi.org/10.3389/fonc.2021.772052