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Directional reorientation of migrating neutrophils is limited by suppression of receptor input signaling at the cell rear through myosin II activity
To migrate efficiently to target locations, cells must integrate receptor inputs while maintaining polarity: a distinct front that leads and a rear that follows. Here we investigate what is necessary to overwrite pre-existing front-rear polarity in neutrophil-like HL60 cells migrating inside straigh...
Autores principales: | Hadjitheodorou, Amalia, Bell, George R. R., Ellett, Felix, Shastry, Shashank, Irimia, Daniel, Collins, Sean R., Theriot, Julie A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595366/ https://www.ncbi.nlm.nih.gov/pubmed/34785640 http://dx.doi.org/10.1038/s41467-021-26622-z |
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