Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation

Homeodomain-interacting protein kinases (HIPKs) belong to the CMGC kinase family and are closely related to dual-specificity tyrosine phosphorylation-regulated kinases (DYRKs). HIPKs are regulators of various signaling pathways and involved in the pathology of cancer, chronic fibrosis, diabetes, and...

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Detalles Bibliográficos
Autores principales: Kaltheuner, Ines H., Anand, Kanchan, Moecking, Jonas, Düster, Robert, Wang, Jinhua, Gray, Nathanael S., Geyer, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595372/
https://www.ncbi.nlm.nih.gov/pubmed/34785661
http://dx.doi.org/10.1038/s41467-021-26935-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595372/
https://www.ncbi.nlm.nih.gov/pubmed/34785661
http://dx.doi.org/10.1038/s41467-021-26935-z

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