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Optimization of anti-ADAMTS13 antibodies for the treatment of ADAMTS13-related bleeding disorder in patients receiving circulatory assist device support

ADAMTS13 (a disintegrin-like and metalloproteinase with thrombospondin type-1 motif 13)-related bleeding disorder has been frequently observed as a life-threatening clinical complication in patients carrying a circulatory assist device. Currently, treatment modalities for the bleeding disorder are v...

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Detalles Bibliográficos
Autores principales: Ito, Toshihiro, Minamitani, Takeharu, Hayakawa, Masaki, Otsubo, Ryota, Akiba, Hiroki, Tsumoto, Kouhei, Matsumoto, Masanori, Yasui, Teruhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595387/
https://www.ncbi.nlm.nih.gov/pubmed/34785706
http://dx.doi.org/10.1038/s41598-021-01696-3